Use your cell phone to diagnose diseases.

July 31, 2009
Microscopy provides a simple, cost-effective, and vital method for the diagnosis and screening of hematologic and infectious diseases.It is an essential tool in disease diagnosis and widely used all over the world. Unfortunately, the EXPERTISE required to use the tool, and to evaluate the findings is not very common. One requires a pathologist with many years of experience to make sense of those seemingly random and confused pixels. ( I know, i am a pathologist :-)

But the advent of digital imaging has solved many of our troubles. Telepathology made sure that we do not need a pathologist physically present at the site, to render a diagnosis. But microscopy and digital imaging of the biopsy/tissue fragment was still a hassle. Now we have done better. You don’t even need a microscope to send a microscopic image over the network!!Researchers from the Univ. of California worked with high-powered LED – which retails for just a few dollars – coupled with a typical camera phone to produce a clinical quality image sufficient for detecting in a field setting some of the most common diseases in the developing world.

The newly developed technology, CellScope, allows for average cell cameras to be retrofitted with powerful microscopes, able to detect malaria parasites, and even fluorescent marker-stained tuberculosis bacteria.Thus you have your humble cell-phone transformed into the “cell-scope”.

(a) Thick smear of Giemsa-stained malaria-infected blood. (b) Thin smear of Giemsa-stained malaria-infected blood. (c) Sickle-cell anaemia blood smear. White arrows point to two sickled red blood cells. Scale bars are 10 µm.

“The images can either be analyzed on site or wirelessly transmitted to clinical centers for remote diagnosis. The system could be used to help provide early warning of outbreaks by shortening the time needed to screen, diagnose and treat infectious diseases,” University of California in San Francisco (UCSF)/UCB Bioengineering Graduate Group graduate student David Breslauer adds